Season
- Season 0 2012-08-26
- Season 1 2009-07-16
- Season 2 2010-01-14
- Season 3 2010-09-09
- Season 5 2011-09-25
- Season 6 2012-01-08
- Season 7 2012-06-17
- Season 8 2012-09-09
- Season 9 2013-01-06
- Season 10 2013-06-16
- Season 11 2014-01-05
- Season 12 2015-01-04
- Season 13 2016-01-03
- Season 14 2017-01-03
- Season 15 2018-01-07
- Season 16 2019-01-06
- Season 17 2020-01-05
- Season 18 2021-01-03
- Season 19 2022-01-05
- Season 20 2023-01-02
- Season 21 2024-01-07
Episode
- Episode 1: Perez Hilton and Teresa Giudice
- Episode 2: Jenna Dewan Tatum and Heather Thomson
- Episode 3: Nicole Richie and Andrew Rannells
- Episode 4: Kevin Jonas and Lance Bass
- Episode 5: Joanna Krupa and Lea Black
- Episode 6: Jacqueline Laurita & Theresa Caputo
- Episode 7: Ramona Singer & Liz Margulies
- Episode 8: Jeff Lewis & Cloris Leachman
- Episode 9: Cyndi Lauper & Sherri Shepherd
- Episode 10: Marysol Patton, Ana Quincoces and Alexia Echevarria
- Episode 11: Kelly Ripa & Mark Consuelos
- Episode 12: Cat Ommaney and Sonja Morgan
- Episode 13: Jimmy Fallon, Anthony Anderson, Jezsse Bradford and Zach Cregger
- Episode 14: Kerry Heffernan, Tom Cholicchio & Chris Cosentino
- Episode 15: NeNe Leakes & Ellen Barkin
- Episode 16: Joanna Garcia-Swisher & Chrissy Teigen
- Episode 17: Michelle Trachtenberg & Carole Radziwill
- Episode 18: Jenny McCarthy & Donnie Wahlberg
- Episode 19: Ethan Hawke & Liam Neeson
- Episode 20: Brittany Snow & Adriana De Moura
- Episode 21: Wendy Williams
- Episode 22: Vanessa Williams & RuPaul
- Episode 23: Andrew McCarthy & Max Greenfield
- Episode 24: Mike "The Situation: Sorrentino, Pauly D., Vinny Guadagnino and Ronnie Ortiz-Magro
- Episode 25: Kate Gosselin and Morgan Fairchild
- Episode 26: Mario Lopez & Melissa Gorga
- Episode 27: Jill Zarin
- Episode 28: LuAnn de Lesseps & Lauren Conrad
- Episode 29: Gina Gershon & Jackie Warner
- Episode 30: Brandy & Lisa Hochstein
- Episode 31: Caroline Manzo & Yvette Nicole Brown
- Episode 32: Scott Baio & Jamie Lynn Sigler
- Episode 33: Jenni Pulos and Zoila Chavez
- Episode 34: Fabio Viviani, Richard Blais, Jen Carroll and Spike Mendelson
- Episode 35: Larry King & Dreama Walker
- Episode 36: Joanna Krupa & Karent Sierra
- Episode 37: Andy's Hurricane Party
- Episode 38: Ryan Murphy & Mark Consuelos
- Episode 39: Tamar Braxton & Denise Richards
- Episode 40: Jimmy Fallon
- Episode 41: Phaedra Parks & Coco T
- Episode 42: Kyle Richards & Jay Mohr
- Episode 43: Padma Lakshmi & Alicia Silverstone
- Episode 44: Russell Peters & Kandi Burruss
- Episode 45: Brandi Glanville & Willie Geist
- Episode 46: Tyra Banks & Whitney Cummings
- Episode 47: Gail Simmons & Peter Facinelli
- Episode 48: Anna Quincoces & Camille Paglia
- Episode 49: Kenya Moore & Tichina Arnold
- Episode 50: Valerie Bertinelli & Jesse Tyler Ferguson
- Episode 51: Joan Collins & Martyn Lawrence-Bullard
- Episode 52: The Ladies of 'Jersey Shore'
- Episode 53: Lea Black & Erin Andrews
- Episode 54: Reza Farahan & Kim Zolsiac-Bierman
- Episode 55: Kristin Cavallari & Taylor Armstrong
- Episode 56: Lisa Rinna & Jeff Lewis
- Episode 57: Carmen Electra & Billy Ray Cyrus
- Episode 58: Jane Fonda & Sandra Bernhard
- Episode 59: Cynthia Bailey & Golnesa "GG" Gharachedaghi
- Episode 60: Camille Grammer & Julie Chen
- Episode 61: Bethenny Frankel
- Episode 62: Aisha Taylor & Shemar Moore
- Episode 63: Elsa Patton & Mark Consuelos
- Episode 64: Lilly Gallicci & Porsha Stewart
Watch What Happens Live with Andy Cohen - Season 8 Episode 15 : NeNe Leakes & Ellen Barkin
Among other topics they discuss, the main topic of this episode is S2e3 of The Real Housewives of Miami called "a mynt meltdown" with Ellen Barkin & Nene's Leekes.
